Joel Leal

PhD Candidate

Joel Leal

PhD Candidate

A little bit about me...

My research is focused on uncovering the genomic architecture of complex phenotypes and beef quality is my model trait. I am applying bioinformatic tools to multiple phenotypic traits measured in beef cattle from the Multibreed Angus-Brahman population of the University of Florida. From this analysis, the main proteolytic system associated with meat tenderness, μ-calpain and calpastatin, and a number of transmembrane anchoring proteins were identified as associated with meat quality. These anchoring proteins may be proteolytic substrates of the μ-calpain and calpastatin system or they could be involved in adipocyte and myocyte proliferation having a direct effect on eating quality.

 

I am currently working on differential expression analyses for meat quality using RNAseq. Some quantitative trait-associated genes, and differentially expressed genes and isoforms were uncovered. In addition, an eQTLs and sQTLs analysis in skeletal muscle was carried out paying special attention to differentially expressed genes related to meat quality.

Publications

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